Pounding Keys, Not Gavels, to Sell India’s Tea
Pounding Keys, Not Gavels, to Sell India’s Tea
The cacophony of India’s public tea auctions will soon give way to the gentle tapping of keyboards as the country’s tea markets are set to go digital.
Mouse Studies Identify Gene That May Influence Metastasis Risk In Breast Cancer
Researchers have identified a pattern of gene activity in mice that may help to predict individual risk for breast cancer metastasis and survival in humans. A single gene called bromodomain 4 (Brd4) regulates the expression of this pattern, also called a signature.
The Digital Photography Show #30: Win a Wacom Intuos3 6×8, and Macro Photography Fundamentals (24MB, 70mins)
The Digital Photography Show #30: Win a Wacom Intuos3 6×8, and Macro Photography Fundamentals (24MB, 70mins) LISTEN TO THE PODCAST HERE December 14, 2006: Welcome to the Tabletastic Thirtieth of The Digital Photography Show. Today we interview a representative from Wacom, the makers of incredibly useful pen tablet input devices. What is a …
50 Greatest Game Innovations
50 Greatest Game Innovations
From gameplay, to presentation to input devices, videogames are a hotbed of innovation. Here are some that have already made their impact—and others that will shape the future of the medium
Mouse Ears Headband
Instructions for making a headband that looks like mouse ears.
USB Problem In Vista
Last week, Microsoft released an update for Vista’s Windows Defender software and some people reported that their mice and keyboards stopped working after they installed the update. “We are aware of concerns that a recent Microsoft update may be causing problems with USB devices. We are investigating the matter, and at this time, do not have […]
Adesso Multimedia Keyboard Review
Adesso Multimedia Keyboard Review
The “Adesso Multimedia Keyboard and Optical Mouse” is a keyboard made for demanding users who want both mobility and direct multimedia access at the touch of a finger. This keyboard combines quick access multimedia keys, a full-size keyboard, and an optical trackball in one device that is easy to use on your desk at work or your lap at home. Read on to see how this keyboard compares against your standard cramped notebook keyboard and deserves a place on your desk.
Circuit Board Mouse Pad
Here’s a fun and geeky (read: not very user-friendly) computer accessory for those who enjoyed the Circuit Board Cufflinks we covered earlier this month. This mouse pad is made from “a genuine recycled circuit board”. Sounds good? Well - before you hit the ‘Buy’ button, you might want to read the last part: Due to the nature […]
Aluminum Keyboard Firmware Update 1.0
Aluminum Keyboard Firmware Update 1.0
This firmware update addresses an issue with the aluminum Apple Keyboard and the aluminum Apple Wireless Keyboard where a key may repeat unexpectedly while typing.
HP 2133 Mini-Note PC Coming This Month For $499
HP 2133 Mini-Note PC Coming This Month For $499
HP is expected to launch its new HP 2133 Mini-Note PC at the end of this month for $499. The notebook weighs in at a mere 2 pounds and features a 8.9″ 1280×800 LCD screen, VIA C7-M ULV CPU, full QWERTY keyboard, Wifi, Bluetooth, and an integrated web cam. I absolutely love this little notebook, it […]
HP 2133 Mini-Note PC Coming This Month For $499
HP 2133 Mini-Note PC Coming This Month For $499
HP is expected to launch its new HP 2133 Mini-Note PC at the end of this month for $499. The notebook weighs in at a mere 2 pounds and features a 8.9″ 1280×800 LCD screen, VIA C7-M ULV CPU, full QWERTY keyboard, Wifi, Bluetooth, and an integrated web cam. I absolutely love this little notebook, it […]
Acoustica MP3 To Wave Converter Plus
Click the mouse and forget about it! No confusing bit rate calculations or ro…
Gnarls Barkley Moves Release Date Forward
Gnarls Barkley Moves Release Date Forward
Gnarls Barkley, the Grammy-winning, genre-wrecking partnership of artist/producer Danger Mouse and soul sensation Cee-Lo, will release their new album The Odd Couple a couple of weeks early. Initially slated for an April 8th release, The Odd Couple will now be available at various online and physical music retailers across the week of March 18th. “They felt the timing was right to just go for it,” said an unnamed spokesman for the band. “With the shifting seasons, furtive romantic entanglements and…(read more)
Arabic Keyboard Typing Tutor
Arabic Keyboard Typing Tutor
This software is written in order to increase your arabic typing spead, through
Keyboards with Backlit Keys
The Digital Photography Show #30: Win a Wacom Intuos3 6×8, and Macro Photography Fundamentals (24MB, 70mins)
The Digital Photography Show #30: Win a Wacom Intuos3 6×8, and Macro Photography Fundamentals (24MB, 70mins) LISTEN TO THE PODCAST HERE December 14, 2006: Welcome to the Tabletastic Thirtieth of The Digital Photography Show. Today we interview a representative from Wacom, the makers of incredibly useful pen tablet input devices. What is a …
Effect of Interleukin-8 Gene Silencing With Liposome-Encapsulated Small Interfering RNA on Ovarian Cancer Cell Growth Interleukin-8 (IL-8) is a proangiogenic cytokine that is overexpressed in many human cancers. We investigated the clinical and biologic significance of IL-8 in ovarian carcinoma using human samples and orthotopic mouse models. Tumor expression of IL-8 was assessed by immunohistochemistry among ovarian cancer patients (n = 102) with available clinical and survival data. We examined the effect of IL-8 gene silencing with small interfering RNAs incorporated into neutral liposomes (siRNA-DOPCs), alone and in combination with docetaxel, on in vivo tumor growth, angiogenesis (microvessel density), and tumor cell proliferation in mice (n = 10 per treatment group) bearing orthotopic taxane-sensitive (HeyA8 and SKOV3ip1) and taxane-resistant (SKOV3ip2.TR) ovarian tumors. All statistical tests were two-sided. Of the 102 cancer specimens, 43 (42%) had high IL-8 expression and 59 (58%) had low or no IL-8 expression; high IL-8 expression was associated with advanced tumor stage (P = .019), high tumor grade (P = .031), and worse survival (median survival for patients with high vs low IL-8 expression: 1.62 vs 3.79 years; P < .001). Compared with empty liposomes, IL-8 siRNA-DOPC reduced the mean tumor weight by 32% (95% confidence interval [CI] = 14% to 50%; P = .03) and 52% (95% CI = 27% to 78%; P = .03) in the HeyA8 and SKOV3ip1 mouse models, respectively. In all three mouse models, treatment with IL-8 siRNA-DOPC plus the taxane docetaxel reduced tumor growth the most compared with empty liposomes (77% to 98% reduction in tumor growth; P < .01 for all). In the HeyA8 and SKOV3ip1 models, tumors from mice treated with IL-8 siRNA-DOPC alone had lower microvessel density than tumors from mice treated with empty liposomes (HeyA8: 34% lower, 95% CI = 32% to 36% lower [P = .002]; SKOV3ip1: 39% lower, 95% CI = 34% to 44% lower [P = .007]). Compared with empty liposomes, IL-8 siRNA-DOPC plus docetaxel reduced tumor cell proliferation by 35% (95% CI = 25% to 44%; P < .001) and 38% (95% CI = 28% to 48%; P < .001) in the HeyA8 and SKOV3ip1 models, respectively. Increased IL-8 expression is associated with poor clinical outcome in human ovarian carcinoma, and IL-8 gene silencing decreases tumor growth through antiangiogenic mechanisms.
Old Amalfi, New Mouse
Old Amalfi, New Mouse
The road on the Amalfi coast and the Fiat 500 have improved considerably in 50 years. Italian driving has not.
The Digital Photography Show #30: Win a Wacom Intuos3 6×8, and Macro Photography Fundamentals (24MB, 70mins)
The Digital Photography Show #30: Win a Wacom Intuos3 6×8, and Macro Photography Fundamentals (24MB, 70mins) LISTEN TO THE PODCAST HERE December 14, 2006: Welcome to the Tabletastic Thirtieth of The Digital Photography Show. Today we interview a representative from Wacom, the makers of incredibly useful pen tablet input devices. What is a …